Q: Xango is a liquid fruit product made from mangosteen and other fruits. Are there any human studies indicating that mangosteen fruit, containing xanthones, is useful in human health?

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Answer :Known as the queen of fruits, the exotic mangosteen originates in Southeast Asia, where its used in traditional medicine to treat diarrhea, wounds and skin infections. Numerous companies have been promoting the health benefits of juices and supplements made from mangosteen as well as acai, aronia, camu camu, chasteberry, wolfberry and other exotic fruits. Mangosteen fruit is high in organic compounds called xanthones as well as alpha- and gamma-mangostins; various in vitro (test tube) and animal experiments have suggested these compounds might have effects that could translate to human health benefits. But Jeffrey Blumberg, PhD, director of the Antioxidants Research Laboratory at Tufts Jean Mayer USDA Human Nutrition Research Center on Aging, cautions, No clinical trial of mangosteen in the prevention or treatment of a chronic disease has been published in the peerreviewed literature.

Some marketing claims also suggest that mangosteen may be beneficial against cancer. But the Memorial Sloan-Kettering Cancer Center specifically warns, The efficacy and safety of mangosteen products for cancer treatment in humans have not been established.

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