The Rush Memory and Aging Project gathered information on lifestyle and cognitive function for up to 24 years in a cohort of individuals and then collected autopsy data. In a recent analysis of data from 586 individuals a “healthy lifestyle score” was computed based on self-reported smoking, physical activity levels, alcohol consumption, adherence to a healthy dietary pattern (the Mediterranean-DASH Intervention for Neurodegenerative Delay—or MIND—diet), and late-life cognitive activity. The researchers then compared these scores to results of a battery of standardized cognitive tests and brain pathologies seen on autopsy.
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