A. Bess Dawson-Hughes, MD, director of Tufts’ HNRCA Bone Metabolism Laboratory, answers: “I know of no downside to taking the supplements together. The calcium content of most multivitamins is generally less than 200 milligrams, so multivitamins don’t make much contribution to total calcium intake. Total calcium intake for adults (from food and supplement sources) should be 1,000 to 1,200 milligrams per day.”