Answer :Bess Dawson-Hughes, MD, director of Tufts HNRCA Bone Metabolism Laboratory, replies, The answer of course depends upon whom you ask. Neither the IOM nor anyone else expects that the dose needed for this reader to reach 30 ng/ml would cause harm. (The IOM sets the safe upper limit for vitamin D intake at 4,000 IU per day.) With virtually no risk and a good possibility of benefit, it would seem reasonable to take a vitamin D supplement.