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NewsBites June 2011 Issue

Resistant Hypertension? Maybe It’s the Doctor’s Office

So-called “white-coat” hypertension, where blood-pressure readings are higher in the doctor’s office than elsewhere, may be responsible for more than a third of cases classified as “resistant” hypertension. A Spanish study of 8,295 patients in a national hypertension registry found that 37.5% of those diagnosed with resistant hypertension actually had normal blood pressure outside the doctor’s office. Participants all had readings of at least 140 and/or 90 mm Hg despite being treated with full doses of three or more high-blood-pressure medications. Measured in the doctor’s office, the subjects averaged readings of 161/88. But when measured using 24-hour ambulatory monitoring, the overall readings averaged 134/75, and only 62.5% still had blood pressure high enough to qualify as resistant hypertension. Researchers concluded, “Ambulatory blood-pressure monitoring continues to be needed and must be encouraged for a correct diagnosis and management of all hypertensive patients not controlled on three or more antihypertensive drugs.”

TO LEARN MORE: Hypertension, online before print,

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