Extra Niacin Not Effective vs. Heart Disease
Studies of prescription-strength doses also warn of side effects.
If you’re taking high doses of niacin supplements (vitamin B3) in hopes of preventing heart disease, new results from a large international clinical trial of prescription doses of niacin might give you second thoughts. The study, dubbed HPS2-THRIVE, found no benefit compared to placebo, and raised red flags about potentially serious side effects. A new subanalysis of a similar US niacin trial, AIM-HIGH, was published alongside the findings in the New England Journal of Medicine, confirming the incidence of side effects.